Nicotinamide Riboside (NR) is a form of vitamin B3 and a direct precursor to NAD+, a coenzyme central to cellular energy and DNA repair that declines with age. In a randomised, placebo-controlled trial, healthy middle-aged and older adults taking NR showed significantly raised NAD+ levels versus placebo. This formula pairs 250mg NR with 4mg astaxanthin, a potent antioxidant, in each capsule.

One of the most researched anti-ageing molecules available. Paired with the most powerful antioxidant in nature.

NAD+ is a coenzyme found in every cell of your body. It drives energy metabolism, supports DNA repair, and activates sirtuins - a family of proteins involved in regulating the cellular stress response and inflammation. The challenge is that NAD+ levels decline with age, and that decline is associated with reduced energy, slower cellular repair, and increased vulnerability to age-related conditions.

NR: The Best-Evidenced NAD+ Precursor Available.

Nicotinamide Riboside (NR) is one of the most direct and well-studied ways to raise NAD+ levels. Unlike niacin (another B3 form), NR raises NAD+ effectively without the flushing side effects, and it has accumulated one of the strongest human trial records of any NAD+ precursor.

What the research shows

A randomised, double-blind, placebo-controlled crossover trial published in Nature Communications found that NR supplementation in healthy middle-aged and older adults significantly elevated NAD+ levels and was well tolerated, with potential benefits for blood pressure and arterial stiffness. A separate placebo-controlled trial in aged men confirmed NR augments the skeletal muscle NAD+ metabolome and suppresses circulating inflammatory cytokines - relevant for both recovery and long-term health.

Why Astaxanthin alongside NR?

The same logic that makes NMN + Astaxanthin a compelling pairing applies here: NR works to raise NAD+ and support cellular energy and repair; Astaxanthin - reputedly 6,000 times stronger as an antioxidant than Vitamin C and 550 times more effective than Vitamin E - protects cells from oxidative damage in parallel. It also supports skin health, eye function, and exercise recovery in its own right.

NR vs NMN - which should you choose?

NR has a longer and more extensive human clinical trial record. NMN is a step further up the biosynthetic pathway - it converts to NR before becoming NAD+ - and is now accumulating strong evidence of its own. If budget is a consideration, our NMN with Astaxanthin offers 500mg NMN per capsule and is a strong alternative.

Frequently Asked Questions

What does NR do?
It's a form of vitamin B3 and a direct precursor to NAD+, a coenzyme involved in energy metabolism, DNA repair, and sirtuin activation that declines steadily with age.

Is NR proven to work in humans?
A randomised, double-blind, placebo-controlled trial in healthy middle-aged and older adults found NR significantly raised NAD+ levels and was well tolerated, and a separate placebo-controlled trial in aged men found it augmented the skeletal muscle NAD+ metabolome and suppressed circulating inflammatory markers. NR has one of the strongest human trial records of any NAD+ precursor.

What's the difference between NR and NMN?
Both are NAD+ precursors. NR has the longer, more extensive human trial record; NMN sits a step further up the pathway (it converts to NR before becoming NAD+) and is accumulating its own evidence. We stock both.

Why is astaxanthin included?
It's a potent antioxidant that protects cells from oxidative damage in parallel with NR's role in energy and repair, and it supports skin, eye, and exercise recovery in its own right.

How many capsules should I take?
1-2 per day. Consult your doctor before use if pregnant, nursing, or taking medication.

Each capsule: 250mg NR + 4mg Astaxanthin. 60 capsules. 1-2 per day.

HPMC vegetable capsule. No unnecessary additives.

Consult your doctor before use if pregnant, nursing, or taking medications.